Multiple Pathways To Avoid Beta Interferon Sensitivity of HIV-1 by Mutations in Capsid
نویسندگان
چکیده
منابع مشابه
Second-site compensatory mutations of HIV-1 capsid mutations.
The human immunodeficiency virus (HIV) capsid (CA) protein assembles into a hexameric lattice that forms the mature virus core. Contacts between the CA N-terminal domain (NTD) of one monomer and the C-terminal domain (CTD) of the adjacent monomer are important for the assembly of this core. In this study, we have examined the effects of mutations in the NTD region associated with this interacti...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 2019
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.00986-19